Comments on: Can You Take Psychedelics With Antidepressants?

By: Bob

Bob — Sun, 20 Nov 2022 16:48:48 +0000

In reply to Patrick Dieter. That's not true--especially among younger docs. All my docs know and I use that conversation as an opportunity to educate THEM. Their response is a kind of litmus test. If they clutch their pearls, I find a different doctor.

By: Trevor

Trevor — Fri, 23 Apr 2021 17:33:59 +0000

From personal experience ssri, snri meds like cymbalta, effexxor, welbutrin, paxil, prozac, all greatly diminishtge full psychedelic Experience. I can consume 10 plus grams of strong psilocybin mushrooms with minimal effect. And dmt has very little effect on me. If you want to nit waste your time and money, you need to completely stop all ssri type meds for at least four weeks to completely rebuild the natural pathways and transmitter sites needed for the tryptamine to stick to. Taking antidepressant drugs restrict the amount of available spots the drug can attach to therefore you dont get the intended effect or benafit. I am 44 and have been using psychedelics like lsd, psilocybin, ketamine (only 1 time at 20) dmt, salvia extract and marijuana. There is so much to be learned through the magical ethnobotanical plants mother earth shares with us. Everything we need is provided by nature, and i believe that if you want to know the truth, you need to investigate for yourself and you will discover the answers that you seek. Life is a mystery for each of us to discover and enjoy as we share this planet with each other. Psychedelics teach us about how life is supposed to be lived, in coordination with all. Peace and love to all my brothers and sisters of pacha mama.

By: Anne-Marié

Anne-Marié — Sun, 11 Apr 2021 12:53:10 +0000

Hi I’ve been on the antidepressant Serdep (100mg) for most of my adult life (am 47 yrs old) and am struggling to wean myself off it. I went cold turkey a few months ago and it was hell, so I went back on Serdep. Shrooms is illegal in South Africa but I have a contact now who gave me 100mg capsules of shrooms as I want to use microdosing to wean myself of Serdep – I would rather use shrooms for the rest of my life than chemical products. I am supposed to take 1x serdep a day – must I use the shrooms together with the serdep and then slowly start to skip the serdep, or what would you advice? I cant speak to my doctor as it is illegal to use and I’ll definitely not get any support. Any suggestion would be highly appreciated.

By: Melanie

Melanie — Tue, 29 Dec 2020 15:59:53 +0000

In reply to Lorraine.

Lorraine,
thank you for your comment. Could you tell me more about that too?
Thank you very much.
Melanie

By: Marian

Marian — Mon, 30 Nov 2020 05:40:44 +0000

In reply to Abra. Abra, with so many drugs already in your system, and with a supporting doctor, I'd strongly recommend approaching him and asking if he can help first. only after that start scouring the internet for answers. Best of luck!

By: Abra

Abra — Thu, 19 Nov 2020 19:00:29 +0000

I have been taking antidepressants for the last seventeen years because of a trauma that I experienced at that time that was too big for me to process.
I am taking 225mg of effexor, 300mg of wellbutrin, and 1/4 of a .5mg clonazepam in the morning. I was taking 125mg of seroquel at bedtime but I’ve been reducing that amount, currently lm taking 50mg and hope to be off of it in the next couple of weeks. My doctor is very supportive and is helping me to reduce the wellbutrin next, then effexor.
I want to begin microdosing mushrooms so that the withdrawal effects of coming off these prescription medicines is lessened…and so that my body learns to feel well in a more natural way.
Any advice is appreciated!

By: Bhakti Bev

Bhakti Bev — Mon, 24 Aug 2020 15:11:27 +0000

In reply to Lorraine. Lorraine, I would love to hear more about your experiences 1.5 years later.

By: Matt Christian

Matt Christian — Sun, 10 May 2020 21:17:01 +0000

I am on 5mg Paxil once a day, and the last 3 times I have taken shrooms I felt nothing more than a slight euphoria and found myself being content with starring at nothing. This is after taking 3 grams of golden teacher extracted psilocybin crystal the last time. The 1st 2 times was dried penis envy @ 2grams. With this his being said, I had absolutely No negative effects.

By: Bob Shaman

Bob Shaman — Sat, 18 Apr 2020 04:45:47 +0000

Effexor has a short half life so you could reduce the dose. Day before by 50% and then skip the day of dosing with shrooms. SSRI’s seem to reduce the effect. I suspect for most folks the whole serotonin syndrome is a bit urban legend- there are NO STUDIES only a case reports, most of which involve other drugs in combinations and are second hand. I have not seen lab data and vitals signs- just “anectodal reports’- so basically hearse. . I have been on SSRI and taken Ayahuasca as well as mushrooms and the effect is less- no serotonin syndrome issues at 75 Effexor. It could be I am just a fast metabolizer. I have notice that low dose sequel seems to reallly block psychedelic effects- so “anti-psychotics “ like Abilify as well seem to block the effects of psychedelics. Of course I don’t recommend you go off your medications. If it has a short half life like Seroquel- it’s out of your system (say a low dose like 50 mg) in about 2 days.

If you are not mentally stable then do not take psychedelics. If you have been stable on your medications for some time, you could wean down over a few days if your drug (that is an SSRI) has a short half life. Antipsychotics will likely block all effects. However those on antidepressants ( as long as not Prozac- long half life) you could cautiously experiment if on low to moderate dosages ( at your own risk of course). Medical science really doesn’t know shit about this- they haven’t done any research and likely won’t anytime soon. I have a pharmacy background- however I still advise use caution.

By: Patrick Dieter

Patrick Dieter — Thu, 09 Apr 2020 00:30:48 +0000

In reply to Tena. Why did you feel the need to stop taking the suboxone? I would never consider it, though I also use it to control chronic pain.